10-5414
BPTES
Größe
£153.00
- SKU:
- 10-5414
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 524.68
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 314045-39-1
- Immunogen:
- Energy production|Glutaminase
- Weitere Details:
- Potent and selective allosteric1 inhibitor of kidney-type glutaminase (GLS1), IC50 = 3.3 uM2. Selective for GLS1 over GLS2, g-glutamyl transpeptidase and glutamate dehydrogenase. Shuts down an alternative energy-generating glutaminolysis pathway in P493 cells under both glucose deprivation or hypoxia.3 Reduces the growth of P493 cell xenografts by 50% over a 10 day treatment.4 BPTES inhibition of glutamine utilization in cancer cells increases PD-L1 expression.5 Clears senescent cells and improves various age-related disorders in a geriatric mouse model.6
- Versandbedingungen:
- Ambient