10-5406
PI-103
Größe
£158.00
- SKU:
- 10-5406
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 348.36
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 371935-74-9
- Immunogen:
- DNA|Kinase
- Weitere Details:
- A potent inhibitor of PI-3 kinase, mTOR and DNA-PK, IC50 = 8, 88, 150, 48, 20, 83 and 2 nM for p110A Alpha, p110B Beta, p110G Gamma, p110D Delta, mTORC1, mTORC2 and DNA-PK respectively.1,2 Synergizes with arsenic disulfide to eradicate AML stem cells by induction of differentiation.3 Inhibits the growth of gefitinib-resistant non-small cell lung cancer cell lines.4 Induces autophagy in drug-resistant glioma.5 Protects against a-synuclein-induced toxicity in human neurons by induction of macroautophagy.6
- Versandbedingungen:
- Ambient