CID16020046

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£158.00

SKU:: 10-5362
Physischer Zustand:: Solid
Molekulargewicht:: 425.44
Reinheit:: >98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 834903-43-4
Immunogen:: GPCR
Weitere Details:: CID16020046 is a selective GPR55 antagonist.1 In HEK293 cells expressing GPR55, the compound behaves as an antagonist on lysophosphatidylinositol (LPI)-mediated Ca2+ release but was inactive on cells expressing CB1 and CB2. It blocks LPI-induced migration of colon cancer cells.2 It displays protective effects against oxidized LDL-induced inflammation3, mitigates advanced glycation end products-induced chondrocyte activation4, and displays anti-inflammatory effects in various cells5,6. A useful tool for studying the role of GPR55 in cellular physiology.