10-5296
Ascochlorin
Größe
£163.00
- SKU:
- 10-5296
- Zusätzliche Namen:
- Ilicicolin D|NSC 287492
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 404.93
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 26166-39-2
- Immunogen:
- Cytochrome/MDR
- Weitere Details:
- Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5
- Versandbedingungen:
- Ambient