10-5157
C-DIM 8
Größe
£139.00
- SKU:
- 10-5157
- Zusätzliche Namen:
- DIM-C-pPhOH
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 338.41
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 151358-47-3
- Immunogen:
- ER/Golgi|Protein methyltransferase|Transcription factor
- Weitere Details:
- C-DIM 8 is an antagonist of the orphan nuclear receptor Nur77 (NR4A1, TR3).1 Induces reactive oxygen species and ER stress in pancreatic cancer cells.2 C-DIM 8 mimics the effect of Nur77 knockdown in non-small-cell lung cancer A549 and H460 cells, inhibiting cell growth and inducing apoptosis which was accompanied by decreased expression of survivin and inhibition of mTORC1 signaling.3 Inhibits the expression of B Beta1- and B Beta3-integrin and blocks integrin-dependent breast cancer cell migration.4 Decreases expression of the histone methyltransferase G9A (EHMT2) in a variety of cancer cell lines.5
- Versandbedingungen:
- Ambient