Filgotinib

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£163.00

SKU:: 10-5145
Zusätzliche Namen:: GLPG0634|GS-6034
Physischer Zustand:: Solid
Molekulargewicht:: 425.50
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 1206161-97-8
Immunogen:: Kinase
Weitere Details:: Potent and selective JAK1 inhibitor (IC50s=10, 28, 810 and 116 nM for JAK1, JAK2, JAK3 and TYK2 respectively.2 Displays potent anti-inflammatory activity in various models.1,2 Effective as a monotherapy in patients with active rheumatoid arthritis.3 Reverses oncostatin M-mediated inhibition of rat stem Leydig cell differentiation.4