10-5085
Remodelin
Größe
£163.00
- SKU:
- 10-5085
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 282.36
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 949912-58-7
- Immunogen:
- Acetyltransferase|Cytoskeleton
- Weitere Details:
- Potent and selective inhibitor of N-acetyltransferase 10 (NAT10) which is capable of acetylating microtubules and histones.1 Improves nuclear architecture, chromatin organization and fitness of both human lamin A/C-depleted cells and Hutchinson-Gilford progeria syndrome patient cells1, normalizing progeric and aging cells2. Enhances health span in a mouse model of human accelerated aging syndrome.3 Significantly reduces many of the defects associated with accumulation of the lamin A precursor, prelamin A.4 Inhibits NAT10-promoted metastasis which may be mediated by endothelial-to-mesenchymal transition in hepatocellular carcinoma.5
- Versandbedingungen:
- Ambient