10-5063
Lopinavir
Größe
£139.00
- SKU:
- 10-5063
- Zusätzliche Namen:
- A-157378|ABT-378
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 628.81
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 192725-17-0
- Immunogen:
- Protease
- Weitere Details:
- Lopinavir (192725-17-0) is a potent and selective inhibitor of HIV-1 protease (IC50 = 6.5 nM, HIV cultured in peripheral blood mononuclear cells; Ki = 1.3 pM) which is highly selective over mammalian proteases.1 Lopinavir suffers from poor bioavailability due to extensive cytochrome P450-mediated metabolism. Thus, combination with ritonavir suppresses metabolism and is a preferred regimen for treatment of HIV infection.2 Inhibits replication of SARS CoV-2 virus in vitro, IC50 = 26.63 uM.3
- Versandbedingungen:
- Ambient