10-4976
PAT-1251
Größe
£192.00
- SKU:
- 10-4976
- Zusätzliche Namen:
- Lenumlostat hydrochloride
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 435.8
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2098884-53-6
- Immunogen:
- Lysyl oxidase
- Weitere Details:
- PAT-1251 is a potent (IC50 = 710 nM) inhibitor of LOXL2, a copper-dependent amine oxidase that deaminates lysine and hydroxylysine residues in collagen and elastin. It displayed >400-fold selectivity over LOX as well as high selectivity against the related amine oxidases SSAO, DAO, and MAO-A/B. A potential new therapeutic for the treatment of fibrotic diseases.
- Versandbedingungen:
- Ambient