10-4917
Olutasidenib
Größe
£187.00
- SKU:
- 10-4917
- Zusätzliche Namen:
- FT-2102
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 354.79
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1887014-12-1
- Immunogen:
- Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, KGDH, PDH, and MDH)|Energy production
- Weitere Details:
- Olutasidenib is a potent (IC50's cell-based IDH1 mutants: HCT116-R132H = 21 nM; HCT116-IDH-R132C = 94 nM; U87MG-R132L = 42 nM; U87MG-R132G = 6 nM; U87MG-R132S = 9 nM) and CNS-penetrant mutant isocitrate dehydrogenase 1 inhibitor.1 It induced durable and complete remissions in relapsed or refractory IDH1 mutated acute myeloid leukemia.2,3
- Versandbedingungen:
- Ambient