10-4897
Fexaramine
Größe
£158.00
- SKU:
- 10-4897
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 496.65
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 574013-66-4
- Immunogen:
- Transcription factor
- Weitere Details:
- Fexaramine is a potent (EC50 = 25 nM) and selective agonist of the nuclear bile acid receptor FXR.1 It significantly enhanced osteoblastic differentiation and suppressed osteoclast differentiation from bone marrow macrophages.2 Fexaramine induces enteric FGF15 and reduces diet-induced weight gain, body-wide inflammation, and hepatic glucose production while enhancing thermogenesis and browning of white adipose tissue.3 It protected mice from ethanol-induced liver injury4 and decreased lipid accumulation via hepatic fatty acid oxidation5.
- Versandbedingungen:
- Ambient