10-4836
LDN-192960 HCl
Größe
£153.00
- SKU:
- 10-4836
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 401.35
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 184582-62-5
- Immunogen:
- Kinase
- Weitere Details:
- LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3
- Versandbedingungen:
- Ambient