10-4813
Quizartinib
Größe
£149.00
- SKU:
- 10-4813
- Zusätzliche Namen:
- AC220
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 560.67
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 950769-58-1
- Immunogen:
- Cytochrome/MDR|Kinase
- Weitere Details:
- Quizartinib is a potent and selective inhibitor of FLT3 (Kd = 1.6nM, IC50 = 0.56 nM MV4-11 cells).1 It is in clinical trials for treatment of Acute Myelogenous Leukemia (AML).2,3 Quizartinib priming resulted in prevention of myelosuppression in mice treated with 5-FU and Gemcitabine.4 Quizartinib showed significant reversal of ABCG2-mediated multidrug resistance (@ 3 uM) via antagonism of drug efflux function.5,6
- Versandbedingungen:
- Ambient