10-4784
Fruquintinib
Größe
£158.00
- SKU:
- 10-4784
- Zusätzliche Namen:
- HMPL-013
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 393.40
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1194506-26-7
- Immunogen:
- Kinase
- Weitere Details:
- Fruquintinib is a potent and highly selective inhibitor of VEGFR kinase (IC50's: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM).1 It potently inhibited VEGF/VEGFR signaling and cell proliferation in HUVECs and HLECs and prevented angiogenesis in vitro. Fruquintinib is currently is several clinical trials against metastatic colorectal cancer2 and nonsquamous non-small-cell lung cancer3.
- Versandbedingungen:
- Ambient