10-4765
IPA-3
Größe
£163.00
- SKU:
- 10-4765
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 350.45
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 42521-82-4
- Immunogen:
- Kinase
- Weitere Details:
- IPA-3 is a selective allosteric inhibitor of Group 1 p21-activated kinase (PAK1 IC50 = 2.5 uM)1 via covalent binding to the PAK1 regulatory domain preventing binding to the upstream activator Cdc422. IPA-3 has been shown to induce cell death in human leukemic cell lines3, significantly inhibit TGFB Beta1-induced prostate cell epithelial to mesenchymal transition4 and inhibits the growth of liver cancer cells5.
- Versandbedingungen:
- Ambient