10-4764
LDN-193189 HCl
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£158.00
- SKU:
- 10-4764
- Zusätzliche Namen:
- DM-3189
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 479.4
- Reinheit:
- 99%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1435934-00-1
- ABP:
- No Import Docs
- Immunogen:
- Kinase
- Weitere Details:
- LDN-193189 2HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripotent stem cells.2-3 LDN-193189 HCl has also been used to examine the role of osteogenesis in prostate tumor metastases in bone.4
- Versandbedingungen:
- Ambient