10-4761
GSK583
Größe
£139.00
- SKU:
- 10-4761
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 398.45
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1346547-00-9
- Immunogen:
- Kinase
- Weitere Details:
- GSK583 is a highly selective and potent inhibitor of RIP2 kinase, IC50 = 5 nM human and IC50 = 2 nM rat.1 It also potently Inhibits isolated RPI3 kinase (IC50 = 5 nM) but is inactive against RIP3 in cellular assays due to a very low KM,ATP. GSK583 blocks NOD2 signaling by interfering with XIAP-RIP2 binding resulting in decreased cytokine and chemokine production.1,2
- Versandbedingungen:
- Ambient