iGP-1

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£149.00

SKU:: 10-4747
Physischer Zustand:: Solid
Molekulargewicht:: 309.32
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 27031-00-1
Immunogen:: Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, KGDH, PDH, and MDH)
Weitere Details:: A potent and cell permeable inhibitor of the mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 M, which is selective over the cytosolic enzyme1. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.1