10-4742
CB-103
Größe
£139.00
- SKU:
- 10-4742
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 242.32
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 218457-67-1
- Immunogen:
- Transcription factor
- Weitere Details:
- Orally active inhibitor of the Notch signaling activation complex (IC50's from 0.9 to 3.9 uM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines. CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with G Gamma-secretase Notch inhibitors.
- Versandbedingungen:
- Ambient