10-4714
KC7F2
Größe
£158.00
- SKU:
- 10-4714
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 570.38
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 927822-86-4
- Immunogen:
- Transcription factor
- Weitere Details:
- KC7F2 is an inhibitor of HIF-1A Alpha (IC50 = 20 uM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1A Alpha protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1A Alpha protein synthesis.
- Versandbedingungen:
- Ambient