Ezatiostat

Größe

£163.00

SKU:: 10-4711
Zusätzliche Namen:: TER199|TLK199
Physischer Zustand:: Solid
Molekulargewicht:: 529.65
Reinheit:: 98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 168682-53-9
Immunogen:: Glutathione
Weitere Details:: Ezatiostat is a peptidomimetic inhibitor of glutathione S-transferase P1-1 (GSTP1).1,2 It showed significant hematopoietic stimulatory activity possibly via JNK activation through disruption of the GSTP/JNK interaction.3 Ezatiostat displayed efficacy in treating myelodysplastic syndrome.4,5 Combined treatment with ezatiostat and a PRDX6 inhibitor displayed synergistic effects in the treatment of neuroblastoma in vitro and in vivo.6