Selonsertib

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£149.00

SKU:: 10-4696
Zusätzliche Namen:: GS-4997
Physischer Zustand:: Solid
Molekulargewicht:: 445.5
Reinheit:: 98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 1448428-04-3
Immunogen:: Cytochrome/MDR|Kinase
Weitere Details:: Potent Apoptosis signal-regulating kinase 1 (ASK1) inhibitor (pIC50 = 8.3)1 found to improve metabolic parameters in nonalcoholic steatohepatitis, reduce hepatic steatosis, inflammation, and fibrosis2-4. Selonsertib suppressed the efflux function of multidrug resistance (MDR) transporters ABCB1 and ABCG2.5