Glumetinib

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£187.00

SKU:: 10-4690
Zusätzliche Namen:: SCC244
Physischer Zustand:: Solid
Molekulargewicht:: 459.48
Reinheit:: 98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 1642581-63-2
Immunogen:: Kinase
Weitere Details:: Highly selective (2400-fold selectivity against a panel of 312 kinases) and potent (IC50 = 0.42 nM) inhibitor of c-Met kinase. It induced tumor regression in MET-driven CDX (MKN-45, SNU-5, EBC-1) and PDX (4 NSCLC, 5 HCC) tumor models.