10-4676
R428
Größe
£163.00
- SKU:
- 10-4676
- Zusätzliche Namen:
- Bemcentinib|BGB324
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 506.64
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1037624-75-1
- Immunogen:
- Kinase
- Weitere Details:
- R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM).1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function - combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
- Versandbedingungen:
- Ambient