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10-4675

AZ20

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£153.00

SKU:
10-4675
Physischer Zustand:
Solid
Molekulargewicht:
412.51
Reinheit:
98%
Aufreinigung:
HPLC Purified
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
1233339-22-4
Immunogen:
Kinase
Weitere Details:
AZ20 is a potent and highly selective inhibitor of Ataxia telangiectasia mutated and RAD3-related (ATR) kinase (IC50 = 5 nM in vitro; IC50 = 50 nM in HT29 colorectal adenocarcinoma cells).1 Combination therapy with AZ20 and gemcitabine resulted in synergistic inhibition of tumor cell growth and cell death initiation in pancreatic cancer cell lines.2
Versandbedingungen:
Ambient