10-4672
Luminespib
Größe
£144.00
- SKU:
- 10-4672
- Zusätzliche Namen:
- NVP-AUY922|VER-52296
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 465.54
- Reinheit:
- >99%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 747412-49-3
- Immunogen:
- HSP (Heat shock protein)
- Weitere Details:
- Luminespib is a potent inhibitor (IC50 = 21 nM) of HSP90.1 It is active against various human tumor xenograft models acting via several processes including cytostasis, apoptosis, invasion, and angiogenesis.2,3 Luminespib enhances tumor susceptibility to T-cell-based immunotherapy by re-invigorating the cancer-immunity cycle in NANOG+ cancer cells.4 It also acts as a radiosensitizer against various tumor cells.5-7
- Versandbedingungen:
- Ambient