Liproxstatin-1

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£153.00

SKU:: 10-4670
Physischer Zustand:: Solid
Molekulargewicht:: 340.85
Reinheit:: 98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 950455-15-9
Immunogen:: Antioxidant
Weitere Details:: Liproxstatin-1 is an inhibitor of ferroptosis (IC50 = 22 nM).1 It was able to mitigate tissue injury in a mouse model of hepatic ischemia/reperfusion injury.1 It protected mouse myocardium against ischemia/reperfusion injury via a decrease in VDAC1 and restoration of GPX4 levels.2 Liproxstatin-1's mechanism of activity has been attributed to its activity as a radical-trapping antioxidant.3