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10-4635

PF-9366

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£158.00

SKU:
10-4635
Physischer Zustand:
Solid
Molekulargewicht:
350.85
Reinheit:
98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
72882-78-1
Weitere Details:
PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50's of 1.2 uM and 225 nM respectively.
Versandbedingungen:
Ambient