7alpha-Hydroxycholesterol

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£139.00

SKU:: 10-4538
Physischer Zustand:: Solid
Molekulargewicht:: 402.66
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 566-26-7
Immunogen:: TLR (Toll-like receptor)
Weitere Details:: Metabolite resulting from the action of cholesterol 7 alpha-hydroxylase on cholesterol. 7A Alpha-Hydroxycholesterol is the first intermediate and a rate-limiting step in the major pathway for bile acid synthesis in humans. A pro-inflammatory mediator which upregulates production of CCL2 and MMP9 in macrophages and may promote progression of atherosclerosis.2,3 Possible biomarker for cellular lipid peroxidation.4