10-4495
TWS119
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- SKU:
- 10-4495
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 318.34
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 601514-19-6
- Immunogen:
- Kinase
- Weitere Details:
- TWS-119 is a potent inhibitor of GSK-3B Beta (IC50 = 30 nM).1 At higher concentrations (400 nM), it induces neurogenesis in mouse embryonic stem cells.1 It maintained hepatic stellate cells in the quiescent state.2 TWS119 treatment increased the amount of stem cell-like memory CD8+ T cells3, enhanced metabolic fitness of CD8+ T cells4, and prevented CD8+ differentiation5. It displayed neuroprotective effects in models of cerebral ischemia.6,7 TWS119 greatly increased the efficacy of NK cells against myeloma.8
- Versandbedingungen:
- Ambient