10-4473
Linrodostat
Größe
£163.00
- SKU:
- 10-4473
- Zusätzliche Namen:
- BMS-986205
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 410.92
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1923833-60-6
- Immunogen:
- Tryptophan
- Weitere Details:
- Linrodostat is an irreversible inhibitor (IC50 = 1.1 nM HEK293 cells; 1.7 nM HeLa cells) of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme that metabolizes tryptophan into immunosuppressive kynurenine.1,2,3 Acts synergistically with PD-1 inhibitors in various cancer models including bladder4, advanced solid tumors5, and hematologic5.
- Versandbedingungen:
- Ambient