T863

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£177.00

SKU:: 10-4460
Physischer Zustand:: Solid
Molekulargewicht:: 394.48
Reinheit:: 98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 701232-20-4
Weitere Details:: T863 is a potent (IC50 = 49 nM CPM fluorescent assay; 17 nM TLC assay) and selective (against DGAT2 and MGATs 2 and 3) inhibitor of diacylglycerol transferase 1 (DGAT1). In mice, it caused weight loss, increased insulin sensitivity, alleviated hepatic steatosis, and reduced triglyceride and cholesterol levels.