10-4436
Moxidectin
Größe
£149.00
- SKU:
- 10-4436
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 639.83
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 113507-06-5
- Immunogen:
- Transcription factor
- Weitere Details:
- Moxidectin is a macrocyclic lactone anthelmintic drug used in veterinary medicine for the treatment of various parasitic diseases. In 2018, It was approved for use in the treatment of river-blindness in humans.1 Moxidectin is also being investigated as a possible treatment for scabies in humans.2 Moxidectin inhibited the proliferation of several glioblastoma multiforme (GBM) cell lines via induction of apoptosis.3 It inhibited the MEK-ERK pathway resulting in blocking of nuclear translocation and transcription of the YAP/TAZ-TEAD complex in GBM cells. It suppressed growth of GBM tumors by 90% in an intracranial tumor model.
- Versandbedingungen:
- Ambient