TH257

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£158.00

SKU:: 10-4418
Physischer Zustand:: White to off-white glassy solid
Molekulargewicht:: 422.54
Reinheit:: >98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 2244678-29-1
Immunogen:: Cytoskeleton|Kinase
Weitere Details:: TH257 is a potent (IC50's = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.