10-4393
MIF20
Größe
£168.00
- SKU:
- 10-4393
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 238.25
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1191288-81-9
- Weitere Details:
- MIF20 is a macrophage inhibitory factor (MIF) agonist (2.5 fold increase in MIF bound to its receptor @ 500 nM).1 It augments MIF-dependent AMPK signaling and limits ischemic cardiac injury. MIF20 protected the heart from ischemia-reperfusion injury via MIF-mediated activation of AMPK.2 It decreased infarct size and preserved systolic function. MIF20 also augments protective metabolic responses by reducing the NADH/NAD ratio leading to a decrease in the accumulation of reactive oxygen species.
- Versandbedingungen:
- Ambient