10-4386
SG-55
Größe
£168.00
- SKU:
- 10-4386
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 319.36
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Weitere Details:
- SG-55 is a noncompetitive AKR1C3 inhibitor (IC50 = 5 nM) with high selectivity over other isoforms. It synergized with Osimertinib in EGFR mutant cancer cells to suppress cell proliferation, clonogenicity, and survival. SG-55 resensitized PC-9/OR triple mutant NSCLC cells to Osimertinib treatment. Active in vivo.
- Versandbedingungen:
- Ambient