10-4371
Indacaterol maleate
Größe
£139.00
- SKU:
- 10-4371
- Zusätzliche Namen:
- QAB149
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 508.57
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 753498-25-8
- Immunogen:
- GPCR|RNA
- Weitere Details:
- Indacaterol maleate is a full agonist (pEC50 = 8.06) of the human B Beta2 adrenoceptor.1,2 Clinically important drug for the treatment of chronic obstructive pulmonary disease. Indacaterol blocked colorectal cancer progression in vitro (IC50 = 19.01 uM) and in vivo via inhibition of the splicing factor SRSF6 by binding to its RRM2 domain.3 It also blocked cell migration in metastatic breast cancer MDA-MB-231 cells by a similar mechanism.4
- Versandbedingungen:
- Ambient