10-4364
TAK-063
Größe
Auf Anfrage
- SKU:
- 10-4364
- Zusätzliche Namen:
- Balipodect
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 428.43
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1238697-26-1
- Immunogen:
- PDE (Phosphodiesterase)
- Weitere Details:
- TAK-063 is a potent (IC50 = 0.3 nM), selective, and orally bioavailable inhibitor of phosphodiesterase 10A (PDE10A).1 It increased levels of cAMP and cGMP in mice and suppressed PCP-induced hyperlocomotion in mice. TAK-063 displayed antipsychotic-like activity in rats.2 It also displayed neuroprotective effects and ameliorated behavioral deficits in a mouse model of Huntington's Disease.3 TAK-063 has displayed neuroprotective effects in mouse models of ischemic stroke.4,5
- Versandbedingungen:
- Ambient