10-4350
Sotrastaurin
Größe
£168.00
- SKU:
- 10-4350
- Zusätzliche Namen:
- AEB071
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 438.49
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 425637-18-9
- Immunogen:
- Kinase
- Weitere Details:
- Sotrastaurin is a highly selective and potent (IC50's for PKC isotypes: A Alpha = 2.1 nM, B Beta1 = 2.0 nM, D Delta = 1.3 nM, E Epsilon = 6.2 nM, H Eta = 6.1 nM, Q Theta = 1.0 nM) pan-PKC inhibitor.1 Potent immunomodulatory agent that inhibits early T-cell activation and displays potential for the prevention of transplant rejection and the treatment of inflammatory diseases.2,3 Sotrastaurin has anticancer activity in various cancer models including breast4, CLL5, ocular melanoma6, and B-cell lymphoma7.
- Versandbedingungen:
- Ambient