10-4290
ERGi-USU
Größe
£144.00
- SKU:
- 10-4290
- Zusätzliche Namen:
- NSC139021
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 255.30
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1147-56-4
- ABP:
- No Import Docs
- Immunogen:
- Kinase|Transcription factor
- Weitere Details:
- ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.
- Versandbedingungen:
- Ambient