10-4279
RPI-GLYT2-82
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£182.00
- SKU:
- 10-4279
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 443.97
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Immunogen:
- Monoamine receptor
- Weitere Details:
- RPI-GLYT2-82 is a reversible, allosteric antagonist (IC50 = 554 nM) of Glycine Transporter 2 (GLYT2) with selectivity over GLYT1. It is also an antagonist of the serotonin receptor 5-HT2A (IC50 = 1.9 uM). RPI-GLYT2-82 displayed efficacy in the CCI and PSNL mouse models of neuropathic pain. It showed no addiction liability and had no on-target side effects.
- Versandbedingungen:
- Ambient