10-4250
CGP-37157
Größe
£168.00
- SKU:
- 10-4250
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 324.22
- Reinheit:
- 99%
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 75450-34-9
- ABP:
- No Import Docs
- Immunogen:
- Ion channel
- Weitere Details:
- Inhibits the mitochondrial Na+-Ca2+ exchanger (NCX) in isolated heart mitochondria, IC50=0.36 uM.1 Does not inhibit the plasmalemmal NCX.2 Also inhibits voltage-gated Ca2+ channels in intact cells and therefore its use in cellular studies must employ adequate controls.3 Prevents sudden death in a Guinea pig model of heart failure.4 Displays pronounced cytoprotective effects in chromaffin cells5 and in neuronal injury models.6 Blood-brain barrier permeant.
- Versandbedingungen:
- Ambient