10-4227
RGN6024
Größe
£197.00
- SKU:
- 10-4227
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 403.46
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 3055038-20-2
- Immunogen:
- Cytoskeleton
- Weitere Details:
- RGN6024 is an orally bioavailable and brain-penetrant tubulin destabilizer. It inhibits microtubule polymerization by binding to the colchicine binding site of B Beta-tubulin. Active in glioblastoma cell lines with nanomolar potency. RGN6024 was active in vivo in temozolomide-resistant LN-18 and BT142 glioblastoma xenograft models.
- Versandbedingungen:
- Ambient