10-4195
PITSTOP2
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£158.00
- SKU:
- 10-4195
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 473.36
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1332879-52-3
- Immunogen:
- Cytoskeleton|GTPase
- Weitere Details:
- PITSTOP2 inhibits clathrin-mediated endocytosis via blockade of endocytic ligand association with the clathrin terminal domain leading to clathrin coat assembly inhibition.1 It was able to cause a collapse of the nucleocytoplasmic permeability barrier and a reduction of Importin-B Beta binding.2 PITSTOP2 reduced viability in HeLa cells by trapping dividing cells in metaphase through loss of mitotic spindle integrity.3
- Versandbedingungen:
- Ambient