10-4174
Idasanutlin
Größe
£149.00
- SKU:
- 10-4174
- Zusätzliche Namen:
- RG7388
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 616.49
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1229705-06-9
- Immunogen:
- Transcription factor
- Weitere Details:
- Idasanutlin is a potent (IC50 = 6 nM) and selective inhibitor of MDM2, the primary negative regulator of p53.1 It blocks the p53-MDM2 interaction activating the p53 pathway leading to cell cycle arrest and apoptosis. Idasanutlin has displayed efficacy in the treatment of multiple cancers alone and in combination with other chemotherapeutics.2-6
- Versandbedingungen:
- Ambient