LB244

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£197.00

SKU:: 10-4133
Physischer Zustand:: Solid
Molekulargewicht:: 537.58
Reinheit:: >98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
Immunogen:: STING
Weitere Details:: LB244 is a potent (EC50 = 800 nM THP1 cells) and irreversible STING antagonist with markedly enhanced proteome-wide selectivity compared to parent compound BB-Cl-amidine. Potently inhibits STING signaling in vitro in both mouse and human cells and in vivo when formulated in 20% DMSO.