C-176

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£134.00

SKU:: 10-4130
Physischer Zustand:: Solid
Molekulargewicht:: 358.09
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 314054-00-7
Immunogen:: STING
Weitere Details:: C-176 is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. Treatment of Trex-/- mice with C-176 resulted in a significant reduction in serum levels of Type I Interferons and amelioration of systemic inflammation.