10-4119
UNC6934
Größe
£153.00
- SKU:
- 10-4119
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 443.46
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2561494-77-5
- Immunogen:
- Protein methyltransferase
- Weitere Details:
- Potent (IC50 = 104 nM) and selective inhibitor of protein lysine methyltransferase nuclear receptor-binding SET domain-containing 2 (NSD2). It potently binds to the PWWP1 domain antagonizing interaction with nucleosomal H3K36me2. UNC6934 is selective against 14 other human PWWP domains and 33 methyltransferases. Active in a nanoBRET PPI assay in U2OS cells (IC50 = 1.23 uM).
- Versandbedingungen:
- Ambient