10-4116
Marimastat
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- SKU:
- 10-4116
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 331.41
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 154039-60-8
- Immunogen:
- Protease
- Weitere Details:
- Marimastat is an orally bioavailable inhibitor of matrix metalloproteinases (IC50's: MMP-1 = 5 nM, MMP-2 = 6 nM, MMP-3 = 200 nM, MMP-7 = 20 nM, MMP-8 = 2 nM, MMP-9 = 3 nm, MMP-14 = 1.8 nM).1 It has been used to alter the extracellular matrix of the tumor microenvironment in various liposomal3,4 and nano-platforms5-7 along with other therapeutic agents.
- Versandbedingungen:
- Ambient