10-4102
Preladenant
Größe
£168.00
- SKU:
- 10-4102
- Zusätzliche Namen:
- SCH 420814
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 503.57
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 377727-87-2
- Immunogen:
- GPCR
- Weitere Details:
- Preladenant is a potent (Ki = 1.1nM) and selective (>1000-fold over other adenosine receptors) adenosine A2A antagonist.1 It has shown efficacy in rodent and primate models of Parkinsons disease without inducing dyskinesias and displays antidepressant effects.1-3 It has been shown that activation of the adenosine A2A receptor blocks the activation of immune cells and increases the number of regulatory T-cells.4-6 Currently in clinical trials as combination therapy with pembrolizumab.7
- Versandbedingungen:
- Ambient